Abstract
This pilot study explores our first-hand experience using the Combat PRS+ system to deliver Hyperthermic Intraperitoneal Chemotherapy (HIPEC) during cytoreductive surgery. Over the course of five procedures, we observed how the system performed in real surgical conditions, focusing on temperature stability, ease of use, and overall integration into the operating room workflow. In every case, the device maintained a consistent intraperitoneal temperature within the desired range, and no technical issues or delays were encountered. Notably, setup times improved steadily with each procedure, reflecting a positive learning curve. so early findings suggest that the Combat PRS+ system is both reliable and practical for HIPEC delivery. While larger studies are still needed, this initial experience supports its use as a safe and efficient option in complex surgical settings.

This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2025 Professor. Nino Gabunia , Abbas Jaber , Yasmeen sharif mahmoud Mousa
