Neurogenesis in the adult

Abstract

Neurogenesis is the process where the neurons and glial cells can be differentiated from a precursor cells in the nervous tissue. In 1962 Altsman was the first scientist who discovered the new born of neurons in the experiments conducted on rodents. He used the auto-radiographic method after lesions of the brain areas and intracranial injection of thymidine H3 induced proliferation of the cells in this damaged areas. In the different experiments carried on mammals and birds using the same methods and the same substance thymidine H 3 Kaplan and Hinds (1977), Goldman and Nottebohm (1983) shown proliferation of the cells in the dental gyrus and olfactory bulb. So years after Kaplan and Hinds, Goldman and Nottebohm confirmed this discovery. Current evidence (Blackmore, et. al., 2012) shows that even GH supplies neorpgenesis in the experiments in vivo and in vitro. And much more in specific regions of the brain the neurons can be generated daily by different external and internal stimuli factors. Approximately 700 new neurons (Kirsty L, et. al,2015) daily are generated in the hippocampus, sub ventricular zone, and the dentate gyrus , where the mesenchymal cells or neuro stem cells differentiate and migrate to the potential aimed zone. According to collecting data daily activity, dietary and mood effect neurogenesis: daily physical activity , sexual activity, inserting new information (reading) on a daily basis or communicate with new people and especially a good night sleep can significantly stimulate neurogenesis. This researches have the impact at the modern medicine to cure many diseases which happen in the brain (Alzheimer), brain. traumas. And lesions. Despite the odds this researches are developing till now days and the obtained results may be applied in the clinics.